An NRCP study shows how mangrove organisms could fight against the prominent disease in dairy animals – mastitis.

To help the dairy farmers, alternative solutions and medications are still being discovered against diseases that are common to dairy animals. The National Research Council of the Philippines’ basic research has come up with a new information in the introduction to production of antibiotics from mangroves against the commonly endemic disease in dairy animals called Mastitis. Mastitis costs dairy farmers a massive amount for medication of dairy animals, and if not treated, could lead to death.

Mastitis is a dairy cattle disease characterized by the inflammation of the mammary gland and udder tissues which reduces milk production and quality. It is a major endemic disease of dairy cattle. It usually occurs as an immune response to bacterial invasion present in the farm. It constitutes the main causes of economic losses and reasons why antibiotics are utilized in the dairy industry.

Colonies of actinomycetes appeared on the dilution plates using the soil samples collected from various mangrove areas across the country

Several dairy industries encounter dilemma on how this can be further treated with a minimal budget, hence, affordable to most dairy farmers The project of Dr. Irene A. Papa, “Characterization and Production of Secondary Metabolites from Actinomycetes Isolated from Rare Environments against Methicillin-Resistant Staphylococcus aureus in Livestock.” has discovered a low-cost antibiotic from mangroves that can fight against Methicillin-Resistant Staphylococcus aureus (MRSA), which causes Mastitis in cows. Colonies of actinomycetes appeared on the dilution plates using the soil samples collected from various mangrove areas across the country

The bioactive compounds were isolated from actinomycetes found in 10 mangrove areas in 10 provinces across the country. Out of 272 actinomycetes and studied, 19 of which inhibited five strains of MRSA while 14 showed activity against the others. Actinomycetes are microorganisms which produces metabolites acting as antibiotics, anti-tumor agents, immunosuppressive agents (or anti-rejection drugs often used by liver, kidney or heart transplant patients) and enzymes. It is one of the most efficient group of microbes that produce bioactive compounds that have valuable medical, veterinary and agricultural applications.

The NRCP research output has a potential to be a new line of drugs for veterinary health to be made as antibiotic cream, ointment, injectable for treatment of the mastitis disease of dairy cows.

One of the policies that could be generated in the project is the protection of mangroves as sites for sources of bioactives or substances with biological effect against important pathogens.

The result of this project of Dr. Papa was presented on February 12, 2020 at Zamboanga State College of Marine Sciences and Technology during the conduct of the NRCP Regional Basic Research Caravan in Region IX.